Unexpected Desilylative-alkylation of 3-O-tert-Butyl-dimethylsilyl Galangin

2008 Bulletin of the Korean Chemical Society (Print)  
Scheme 2. Proposed mechanism of desilylative-alkylation. Scheme 4. Synthesis of 7-O-alkyl galangin. Reagents and Conditions: a) BBr3, CH2Cl2, rt; b) Ac2O, pyr, rt; c) Imidazole, PhSH, NMP, 0 o C; d) RBr, K2CO3, acetone, rt; e) NH3/MeOH, rt Figure 3. 2D-NOESY result of compound 19.
doi:10.5012/bkcs.2008.29.9.1667 fatcat:m2fj76wdj5gobaafs72sd3yfwy