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Lipoproteome screening of the Lyme disease agent identifies novel inhibitors of antibody-mediated complement killing
[article]
2021
bioRxiv
pre-print
Spirochetal pathogens such as the causative agent of Lyme disease, Borrelia burgdorferi sensu lato, encode an abundance of lipoproteins; however, due in part to their evolutionary distance from more well-studied bacteria such as Proteobacteria and Firmicutes, very few spirochetal lipoproteins have assigned functions. Indeed, B. burgdorferi devotes almost 8% of its genome to lipoprotein genes and interacts with its environment primarily through the production of at least eighty surface-exposed
doi:10.1101/2021.09.23.461563
fatcat:aeve3qp5hzenxjh6no6hasr5z4