A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Pinpointed Stimulation of EphA2 Receptors via DNA-Templated Oligovalence
International Journal of Molecular Sciences
DNA nanostructures enable the attachment of functional molecules to nearly any unique location on their underlying structure. Due to their single-base-pair structural resolution, several ligands can be spatially arranged and closely controlled according to the geometry of their desired target, resulting in optimized binding and/or signaling interactions. Here, the efficacy of SWL, an ephrin-mimicking peptide that binds specifically to EphrinA2 (EphA2) receptors, increased by presenting up todoi:10.3390/ijms19113482 pmid:30404153 fatcat:6xo6rollcrfobjqh7tijcopmha