Integrins and prostate cancer metastases [chapter]

Mara Fornaro, Thomas Manes, Lucia R. Languino
Prostate Cancer: New Horizons in Research and Treatment  
Integrins have emerged as modulators of a variety of cellular functions. They have been implicated in cell migration, survival, normal and aberrant cellular growth, differentiation, gene expression, and modulation of intracellular signal transduction pathways. In this review article, the structural and functional characteristics of integrins, their expression and their potential role in prostate cancer metastases will be discussed.
doi:10.1007/0-306-48143-x_12 fatcat:p3si5szzonbt7cicjzilojjs6u