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ProceedingsofGermanSocietyforStemCellResearch(PGSSCR) Nanotubediameterdirectsstemcellfate
unpublished
_____________________________________________________________________ We generated, on titanium surfaces, self-assembledlayersofverticallyorientatedTiO2 nanotubes withdefined diameters between15 and 100 nm and show that adhesion, spreading, growth and differentiation of mesenchymal stem cells are critically dependent on the tube diameter. A spacing less than 30 nm with a maximum at 15 nm provided an effective length scale for accelerated integrin clustering / focal contact formation and
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