Structure and design of the Flow Injection Synthesis-FIS were many kind, depend on the both propose and chemical process method. For chemical formation energy estimation propose isothermal tube reactor is one of simple rector, where formation energy could be estimate of the reactor dimension, flow of yield and temperature. Generally Non-Isothermal equations especially Mahadevan equation can be applied to get simply formation energy. The equations have to fractioned until be obtained both flow

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... d temperature parameterin Non-Isothermal. Copy Right, IJAR, 2017,. All rights reserved. ...................................................................................................................... Introduction:-Many kind of the useful Flow Injection Synthesis reactor, one of the FIS is use tube reactor where reactance flowing in the structured tube, with base energy equation; Avrami, Ozawa and Kissinger. The chemical reaction generally in Non-Ishothermal condition, temperature and pressure constante but pH reactanse (salt) and alkaline in variation state. One of the advantage of co-precipitation synthesis of the physical characteristic of yield were easy to identify such as amount of formation energy, both particle size and shape. The reaction and formation of nano-Ferrite material simply done by method co-precipitation in the reaction vessel. The container can be a test tube, flatbed, enclosed tub, etc. To obtain a uniform yield of raw material mixing is done by simultaneously mixing and stirring using a stirrer high speed reaction time with formation and deposition of particles that are relatively short and the possibility of changes in temperature, the formation and growth of particles cannot be uniform. So as to obtain a uniform particle size needed some way special treatment reaction parameters, among others; The composition of the reactance (salt) and the base does not change. Because it is impossible to eliminate time variance is carried approaches such as limiting the amount of reactants with the risk of yielding only slightly. Improve fluid mixing process alkaline and salt with a particle size of yield risk is not very homogeneous. The Yield particles confined in a particular polymer shell template and using of computers to control speed of reaction raw material mixing process. The reaction temperature t [ o C] , pH of the raw material reactants use of non-isothermal reactor tube. ;ρ= density [gr/cm 3 ] ,q= energy/gr [ joule/gr], Q= Total Energy = joule, QE= Energy [joule], dx/dt = velocity ,[ m/sec] , dm/dt= rate = [ gr/det ], dq/dt= energy rate = [joule/sec], K = Avrami Constatnta.,R= Gas