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Phytochemicals Analysis and Cytotoxicity Activity of Ethanol Extract of Litseacubeba Lour.Heartwood

Fujiko M, Dalimunthe A, Masfria M
2020 Asian Journal of Pharmaceutical Research and Development  

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Objective: The purpose of this study was to determine the chemical compounds whichcontained in the ethanol extract and cytotoxic activity ethanol extract of Litseacubeba heartwood induced in T47D cells. Methods: The ethanol extract was extracted by maceration using ethanol 96% solvent. Cytotoxic activity was determined with MTT method and the IC50analyzed using SPSS 23. Results: Phytochemicals screening were showed that the ethanol extract of Litseacubeba heartwood contained
more » ... ds, glycosides, alkaloids, flavonoids, saponins and tannins. The IC50of ethanol extract of Litseacubeba heartwood were 349,57 ±0,35μg/ml in T47D cells. Conclusions: Ethanol extract of Litseacubeba heartwood has activity as an anticancer to T47D cells breast cancer agents.
doi:10.22270/ajprd.v8i1.643 fatcat:7iirgsc2mzfbho3ba5w7pxu7gi
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Fujiko M, Dalimunthe A, Masfria M. "Phytochemicals Analysis and Cytotoxicity Activity of Ethanol Extract of Litseacubeba Lour.Heartwood." Asian Journal of Pharmaceutical Research and Development 8.1 (2020) 14-17