Applications of Cross-linked Poly(4-vinylpyridine/styrene) Copolymer supported Ytterbium(III) Triflate in Mannich-type Reaction:Three Component One-pot Synthesis of β-Aminoketones

2009 Bulletin of the Korean Chemical Society (Print)  
The ytterbium catalyst immobilized on the cross-linked poly(4-vinylpyridine/styrene) copolymer (P/S-Yb) was applied in the Mannich-type, three component one-pot synthesis of β-aminoketones. This catalytic system showed excellent catalytic activity and selectivity which resulted in the exclusive formation of β-aminoketone. The applicability of this immobilized catalyst system was shown by the reusability test and again highlighted by the synthesis of a β-aminoketone library using a broad range of substrates.
doi:10.5012/bkcs.2009.30.3.551 fatcat:4yaqpolzlbaopa6qvs7fi46kcy