A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
Internet Electronic Journal of Molecular Design
Motivation. Eugenol, an antioxidant is used as a fragrance, a flavoring agent, and in dental materials. As an adverse effect, eugenol causes allergic contact dermatitis, possibly due to its prooxidant activity and the formation of eugenol-quinone methide (compound 1). We recently reported that dimer of eugenol, dehydrodieugenol A (compound 2) showed the less cytotoxicity and greater antiinflammatory activity than parent eugenols. Therefore, we examined high-yielding methods of producing dimersfatcat:rkdjh6dxk5b7fescq52jyaocgm