Male Breast Cancer: Case Studies and Literature Review

Zaied Sonia, Khechine Wiem, Abbess Ibtissem, Amina Ben Salem, Aloui Salma, Bargaoui Hayfa, Zoukar Olfa, Mhabrech Houda, Faleh Raja, Laajili Hayet, Daldoul Amira
2017 OALib  
Male breast cancer is a rare disease. In Tunisia, it represents 1% of all breast cancers and 1.6% of Male neoplasia. This work is a retrospective study about 5 male patients with breast cancer, treated in the department of medical oncology at Fattouma Bourguiba University Hospital of Monastir (Tunisia) during a period of 3 years from March 2013 to March 2016. Results showed that: invasive ductual carcinoma was the histological type found in all cases; the Her 2 neu was not overexpressed in all
more » ... erexpressed in all cases; hormone receptors were positive in all patients. Two patients had a locally advanced disease. Two patients were diagnosed with metastatic disease; pulmonary and bone metastases. Three patients who were diagnosed with no metastatic disease have had a mastectomy with Axillary lymph node dissection. Adjuvant chemotherapy was administered in two patients. Loco regional radiotherapy was performed in three patients. Tamoxifen-based hormone therapy was administered in three patients. Two patients were treated with palliative chemotherapy. One patient received two lines of chemotherapy with a global survival of 16 months, while the other received only one line of palliative chemotherapy with a global survival of 2 months. One patient received palliative hormone therapy type Tamoxifen with progression free survival of 7 months. Three patients who received curative treatments are in remission of their disease. To conclude male breast cancer is a rare disease with multiple and varied risk factors. It is similar in its clinical, histological and prognostic characteristics to breast cancer in women but also has different characteristics.
doi:10.4236/oalib.1103695 fatcat:42xcm7djczbr3he4y2bonwcwsi