Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis

Giriraj R. Chandak, Donghao Zhou, E. Shyong Tai, Bo Xi, Xiao Ou Shu, Jaspal S. Kooner, Weihua Zhang, Karen L. Mohlke, Andrew P. Morris, Aline Meirhaeghe, Fumihiko Takeuchi, Hongwei Pan (+5 others)
Genome-wide association studies have identified many obesity/body mass index (BMI)-associated loci in Europeans and East Asians. Since then, a large number of studies have investigated the role of BMI-associated loci in the development of type 2 diabetes (T2D). However, the results have been inconsistent. The objective of this study was to investigate the associations of 11 obesity/BMI with T2D risk and explore how BMI influences this risk.
doi:10.17615/hzsd-r171 fatcat:eooypyhtxfdr3ckurn3ycxeta4