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Linking influenza virus evolution within and between human hosts
[article]
2019
bioRxiv
pre-print
Influenza viruses rapidly diversify within individual human infections. Several recent studies have deep-sequenced clinical influenza infections to identify viral variation within hosts, but it remains unclear how within-host mutations fare in the global viral population. Here, we compare viral variation within and between hosts to link influenza's evolutionary dynamics across scales. Synonymous sites evolve at similar rates at both scales, indicating that global evolution at these putatively
doi:10.1101/812016
fatcat:heqiotsak5dyzaconkvmcmqybq