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Sensitization to the Yeast Malassezia Sympodialis Is Specific for Extrinsic and Intrinsic Atopic Eczema
Journal of Investigative Dermatology
The opportunistic yeast Malassezia sympodialis belongs to the normal cutaneous flora but can also cause IgEmediated sensitization in patients suffering from atopic eczema (AE). We investigated 706 individuals by ImmunoCAPm70 and skin-prick tests with a crude M. sympodialis extract. In AE patients, we further performed skin prick tests, atopy patch tests, ELISA, and peripheral blood mononuclear cells proliferation assays with recombinant M. sympodialis allergens (rMala s 1 and 5-9). In 52/97doi:10.1038/sj.jid.5700431 pmid:16778796 fatcat:ikzt4ugu5jbjnmubhg7g2jxjb4