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Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl− currents
American Journal of Physiology - Cell Physiology
Phosphorylation of P-glycoprotein by PKA and PKC modulates swellingactivated Cl Ϫ currents. Am. J. Physiol. 276 (Cell Physiol. 45): C370-C378, 1999.-Several proteins belonging to the ATPbinding cassette superfamily can affect ion channel function. These include the cystic fibrosis transmembrane conductance regulator, the sulfonylurea receptor, and the multidrug resistance protein P-glycoprotein (MDR1). We measured whole cell swelling-activated Cl Ϫ currents (I Cl,swell ) in parental cells anddoi:10.1152/ajpcell.1999.276.2.c370 fatcat:3qg2wbyocbh6pey2vbemq5rwii