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ToppMiR: ranking microRNAs and their mRNA targets based on biological functions and context
2014
Nucleic Acids Research
Identifying functionally significant microRNAs (miRs) and their correspondingly most important messenger RNA targets (mRNAs) in specific biological contexts is a critical task to improve our understanding of molecular mechanisms underlying organismal development, physiology and disease. However, current miR-mRNA target prediction platforms rank miR targets based on estimated strength of physical interactions and lack the ability to rank interactants as a function of their potential to impact a
doi:10.1093/nar/gku409
pmid:24829448
pmcid:PMC4086116
fatcat:xfiekqshmne4roqwleqep3bc6y