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Systematic inference of highways of horizontal gene transfer in prokaryotes
Computer applications in the biosciences : CABIOS
Motivation: Horizontal gene transfer (HGT) plays a crucial role in the evolution of prokaryotic species. Typically, no more than a few genes are horizontally transferred between any two species. However, several studies identified pairs of species (or linages) between which many different genes were horizontally transferred. Such a pair is said to be linked by a highway of gene sharing. Inferring such highways is crucial to understanding the evolution of prokaryotes and for inferring pastdoi:10.1093/bioinformatics/btt021 pmid:23335015 fatcat:qcbu73lycjcqtkazastdlqnqti