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Experimental models for analysis of oligodendrocyte pathophysiology in stroke
2009
Experimental & Translational Stroke Medicine
White matter damage is a clinically important part of stroke. However, compared to the mechanisms of neuronal injury in gray matter, white matter pathophysiology remains relatively understudied and poorly understood. This mini-review aims at summarizing current knowledge on experimental systems for analyzing the role of white matter injury relevant to stroke. In vitro platforms comprise primary cultures of both mature oligodendrocytes (OLGs) as well as oligodendrocyte precursor cells (OPCs).
doi:10.1186/2040-7378-1-6
pmid:20150984
pmcid:PMC2820444
fatcat:kv6gevefzzckhosv4de522engm