Study of Serum Magnesium Levels in Diabetic Retinopathy

Mohamed Kauser, Asfia Afreen, Jagadeesh Kasi
2014 Journal of Research in Medical and Dental Science  
Hypomagnesaemia has been reported to occur with increased frequency in patients with type 2 diabetes mellitus; it is frequently overlooked and undertreated. Hypomagnesemia has also been associated with diabetic retinopathy. Aims: The present study was conducted with an objective to evaluate the serum magnesium and fasting blood glucose in type 2 Diabetes mellitus cases and compare them with controls. The present study also attempts to evaluate the possible relationship between diabetic
more » ... n diabetic retinopathy and serum magnesium levels. Material and Methods: A total of 120 subjects were included in this study and divided into 3 groups. The study group consisted of 40 patients that are type 2 diabetes and retinopathy and the control groups consisted of 40 patients with type 2 diabetes without retinopathy and 40 healthy subjects respectively. Both cases and controls were subjected to estimation of biochemical parameters. Results: There is significant difference between levels of serum magnesium levels among diabetics without complications and healthy subjects. The mean serum magnesium levels among the above groups are 1.79±0.15 mg/dl and 2.25±0.16 mg/dl respectively (p<0.001). There is also significant difference between levels of serum magnesium levels among diabetic retinopathy patients and diabetics without complications i.e.1.62±0.13mg/dl and 1.79±0.15 mg/dl respectively (p<0.001). Conclusion: The serum magnesium levels were significantly lower in patients with diabetic retinopathy compared to diabetics without complications.
doi:10.5455/jrmds.2014235 fatcat:345v6aadhja5fd745epur42hn4