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Coupling Mechanism and Significance of the BOLD Signal: A Status Report
2014
Annual Review of Neuroscience
Functional magnetic resonance imaging (fMRI) provides a unique view of the working human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects changes in deoxyhemoglobin driven by localized changes in brain blood flow and blood oxygenation, which are coupled to underlying neuronal activity by a process termed neurovascular coupling. Over the past 10 years, a range of cellular mechanisms, including astrocytes, pericytes, and interneurons, have been proposed to play a
doi:10.1146/annurev-neuro-071013-014111
pmid:25032494
pmcid:PMC4147398
fatcat:yrptkxd6xbhubgu3bpnco4xbua