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The soluble sperm factor that activates the egg: PLCzeta and beyond
2020
Reproduction
Preserved Fulltext
PLCzeta(ζ) initiates Ca2+ oscillations and egg activation at fertilization in mammals, but studies in mouse eggs fertilized by PLCζ knockout (KO) sperm imply that there is another slow acting factor causing Ca2+ release. Here, I propose a hypothesis for how this second sperm factor might cause Ca2+ oscillations in mouse eggs.
doi:10.1530/rep-20-0079
pmid:32485666
fatcat:2qccwpehvbfqzfhnubsekfmlmy