Comparison of Clavien-Dindo and Common Terminology Criteria for Adverse Events Classifications in Postoperative Early-Stage Complications of Patients with Colorectal Cancer

Veysel Cem Özcan, Suat Kutun, Kubilay Kenan Özlük, Eda Güner, Bulent Aksel, Lütfi Doğan, Cihangir Özaslan
2022 Acta Oncologica Turcica  
The present study aimed to compare early complication rates, risk factors for complications, and hospital stay lengths in patients operated on for Colorectal cancer, by using Clavien-Dindo and Common Terminology Criteria for Adverse Events (CTCAE) complication classifications. Materials and methods: 222 patients who were operated between March 2019 and June 2020 with the diagnosis of colorectal cancer and had early complications were evaluated retrospectively. Complications that developed in
more » ... early postoperative period were graded according to Clavien-Dindo and CTCAE classifications.The effects of demographic data, surgical technique, tumor location, neoadjuvant chemoradiotherapy history, preoperative transfusion history, urgency of the operation, additional organ resection, co-morbid diseases, pathological stage and duration of surgery on complications were compared. Results: According to the Clavien-Dindo classification, the risk of developing complications was 3 times higher in male gender, 8 times higher in open surgical intervention, and 1.7 times higher in diabetes mellitus. According to the CTCAE classification, performing liver resection in the same session increased the risk of complications 5 times, while the use of open surgical technique increased the risk 8 times. Discussion: Neither classification system is superior to the other in grading postoperative complications, and both can be used to rate surgical complications.
doi:10.5505/aot.2022.67699 fatcat:huqgfwj2yfek5ehqnl67xaz76y