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Positive KL-6 mucin expression combined with decreased membranous β-catenin expression indicates worse prognosis in colorectal carcinoma
1994
Oncology Reports
Interaction of MUC1 with ß-catenin plays a significant role in tumor progression and invasion. However, the clinical significance of coexpression of MUC1 and subcellular ß-catenin expression in colorectal carcinoma remains unclear. The present study evaluated the clinicopathological significance of their combined expression for predicting prognosis. Seventy-seven colorectal carcinomas were subjected to immunohistochemical staining with anti-MUC1 KL-6 mucin and anti-ß-catenin monoclonal
doi:10.3892/or_00000103
fatcat:6cqveildwrbwzdasiref65k33a