Does Zinc Overdose in Rat Diet Alter Cu, Fe, Mn, and Zn Concentrations in a Tapeworm Host?

I. Jankovská, V. Sloup, J. Száková, J. Magdálek, B. Horáková, I. Langrová
2018 Scientia Agriculturae Bohemica  
We evaluated Cu, Fe, Mn, and Zn concentrations in the bone, muscle, testes, intestine, liver, kidneys and tapeworm parasites Hymenolepis diminuta of rats from four groups: 12 animals given zinc lactate (120 mg/rat and week) in feed mixture (M0 group); six animals given zinc lactate (120 mg/rat and week) in feed mixture and infected with tapeworms (MT group); six control animals fed a standard mixture of ST-1 for rats (00 group); and six control animals fed a standard mixture of ST-1 for rats
more » ... infected with tapeworms (0T group). The experiment was conducted over a six-week period. In our study, tapeworm presence decreased element concentrations in the majority of rat tissues. Tapeworms accumulated higher levels of zinc and manganese than did the majority of host tissues; however, they accumulated very little iron and copper in comparison to the host tissues. Zinc overdosing increased manganese concentrations in rat tissues; zinc overdosing also seemed to protect the liver from absorption of Fe by tapeworms.
doi:10.2478/sab-2018-0015 fatcat:4f2bs6kuurbxne73tcpf6u4nnu