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A dual role of the putative RNA dimerization initiation site of human immunodeficiency virus type 1 in genomic RNA packaging and proviral DNA synthesis
Journal of Virology
In retroviruses, the genomic RNA is in the form of a 60S-70S complex composed of two identical genomelength RNA molecules tightly associated through numerous interactions. A major interaction, called the dimer linkage structure, has been found near the RNA 5 end and is probably involved in the control of translation, packaging, and recombination during proviral DNA synthesis. Recently, a small sequence corresponding to a stem-loop structure located in the 5 leader of human immunodeficiencydoi:10.1128/jvi.70.12.8348-8354.1996 fatcat:622bqx5xkbesrhbuksa4m3lkgq