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Refining Dynamic Risk Stratification and Prognostic Groups for Differentiated Thyroid Cancer With TERT Promoter Mutations
Journal of Clinical Endocrinology and Metabolism
Context: Currently, no recurrence or mortality risk systems consider molecular testing when predicting thyroid cancer outcomes. Objective: We developed an integrative prognostic system that incorporates telomerase reverse transcription (TERT) promoter mutations into the recently proposed risk reclassification system after initial therapy [dynamic risk stratification (DRS)] to better categorize and predict outcomes. Design: A total of 357 differentiated thyroid cancer (DTC) patients withoutdoi:10.1210/jc.2016-3434 pmid:28323925 fatcat:ca2r5st4ynglll3zveqqj2n2mu