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Lung Tumours in Rats after Intratracheal Instillation of Dusts
Annals of Occupational Hygiene
Silver nanoparticles (AgNPs) are widely used because of their anti-bacterial and anti-inflammatory properties; however, the adverse health effects of these nanoparticles, especially to the lungs, have been less studied. We thus investigated the inflammatory response of polyvinylpyrrolidone (PVP)-coated AgNPs and silver nitrate (AgNO 3 ) after 24 h, 14 days and 28 days of single intratracheal instillation in rats. The bronchoalveolar lavage fluid (BALF) samples were collected and analyzed; adoi:10.1093/annhyg/38.inhaled_particles_vii.357 fatcat:srpct7misfcdrokepqu263hzgm