Treatment of a Serotype-1 Hepatitis C Virus Infection Using Interferon-Beta in a Patient with a High RNA Titer Who Had Been Receiving Long-Term Hemodialysis Therapy

Shigeru Otsubo, Takahiko Kawata, Masayo Takasaki, Miwa Ishihara, Syuitsu Ueda, Hisayuki Sugimoto, Kimiko Otsubo, Takashi Akiba, Kosaku Nitta, Masanori Hirano
2011 Internal medicine (Tokyo. 1992)  
A serotype-1 hepatitis C virus (HCV) infection in a 67-year-old hemodialysis patient was treated using interferon (IFN)-beta. Although the patient had a high RNA titer (5.1 log IU/mL) and had been receiving longterm hemodialysis therapy (30 years), the initial 4-week IFN-beta administration enabled a rapid virological response without any major adverse effects. However, the final outcome after 24 weeks of IFN beta treatment was classified as unchanged based on the criteria of the Conference on
more » ... ntractable Hepatitis. Here, we describe our experience treating HCV infection using IFN-beta and discuss the indications for such therapy.
doi:10.2169/internalmedicine.50.4453 pmid:21467707 fatcat:3l5vtbce4zdlzjy2lyc3odw2b4