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Antidepressant Use and Risk of Colorectal Cancer in The Women's Health Initative
Colorectal cancer is the third most common cancer among U.S. women; 63,610 new cases were estimated to have occurred in 2015. Prior studies found a reduced risk of colorectal cancer among antidepressant (AD) users, however, none adjusted for depression, which is itself linked to increased colorectal cancer risk and could confound this relationship. We assessed the relationship between ADs and AD drug classes with risk of colorectal cancer in a prospective cohort of 145,190 women between thedoi:10.7275/8423370 fatcat:mzaww6thjvbptj2o2kqw2iu7ti