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Evidence of spreading vasodilation in the human gingiva evoked by nitric oxide
Journal of Periodontal Research
Spreading vasodilation is an important means of increasing local blood flow effectively during increased metabolic demands or in case of vascular injury. Our aim was to develop a technique proving the presence of spreading vasodilation in the human keratinized gingiva. Local vasodilation was evoked by the application of nitric oxide (NO) donor nitroglycerin into a well, fixed 2 mm above the marginal gingiva, in 20 subjects with healthy periodontal tissue. Either 1 or 8 mg/mL nitroglycerindoi:10.1111/jre.12650 pmid:30865289 fatcat:exxsfnkz4jazzasflvuvqj4li4