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Recapitulating folliculogenesis and oogenesis outside the body: encapsulated in vitro follicle growth
Folliculogenesis is a tightly coordinated process essential for generating a fertilization-competent gamete while also producing gonadal hormones that sustain endocrine function. In vitro follicle growth systems have been critical to our understanding of key events in folliculogenesis, such as gonadotropin-independent and -dependent growth, steroid hormone production, and oocyte growth and maturation (cytoplasmic and meiotic). Although there are several successful follicle culture strategies,doi:10.1093/biolre/ioac176 pmid:36136744 pmcid:PMC9843677 fatcat:zr52a4knxjeapl3vy5quddj73m