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Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1
2014
International Journal of Parasitology
Apicomplexan parasites are obligate intracellular pathogens that cause a host of human and animal diseases. These parasites have developed a universal mechanism of invasion involving formation of a 'moving junction' that provides a stable anchoring point through which the parasite invades host cells. The composition of the moving junction, particularly the presence of the protein Apical Membrane Antigen 1 (AMA1), has recently been the subject of some controversy. In this commentary we review
doi:10.1016/j.ijpara.2014.08.001
pmid:25157917
fatcat:zwhd6jhrvnexzl42avvkxkmbyu