Hemophagocytic lymphohistiocytosis associated with H1N1 virus infection and visceral leishmaniasis in a 4.5-month-old infant

Yilmaz Ay, Basak Yildiz, Hale Unver, Deniz Yılmaz Karapinar, Fadil Vardar
2012 Revista da Sociedade Brasileira de Medicina Tropical  
We present a case of a 4.5-month-old boy from Turkey with hemophagocytic lymphohistiocytosis (HLH) associated with H1N1 virus and Leishmania spp. coinfection. Because visceral leishmaniasis can mimic hematologic disorders like HLH, it is important to rule out this clinical condition before starting immunosuppressive therapy. In our case, treatment with liposomal amphotericin B resulted in a dramatic resolution of clinical and laboratory abnormalities.
doi:10.1590/s0037-86822012000300026 fatcat:fx5eim7jfnaz7omcquyr3fp5ti