Predictors of In-Hospital Mortality in Cirrhotic Patients with Spontaneous Bacterial Peritonitis
International Journal of Current Microbiology and Applied Sciences
Spontaneous bacterial peritonitis (SBP) is a major complication of cirrhosis and ascites and is responsible for significant morbidity and mortality, The aim of this work is to determine prognostic factors and scores for SBP-related in-hospital mortality, compare the predictive power of CP, MELD, SOFA and AIMS65scores for the prediction of the mortality also to identify the best score cut-off point. This prospective study included 111 patients (76 males and 35 females) with liver cirrhosis,
... ver cirrhosis, ascites and spontaneous bacterial peritonitis confirmed by laboratory investigations especially peritoneal fluid study was done. There were statistically significant differences between cirrhotic patients with SBP who survive and who don't survive as regard mental status, hepatorenal syndrome, ALT and AST, serum sodium, MELD score, SOFA score and AMS65 score. MELD score and serum sodium have the most excellent prognostic accuracy for SBP-related in-hospital mortality with p= 0.006 for both of them, by identifying cut-off point for MELD score (>25) and for serum sodium (≤126 mEq/L) we can predict mortality in about 73.3 and 93.3 of cirrhotic patients with SBP respectively, as regard serum Sodium and MELD score; the lower the sodium and the higher the MELD score, the more probability for mortality in cirrhotic patients with SBP.