Objective: To investigate the clinical characteristics of omohyoid muscle syndrome for the purpose of decreasing the rate of misdiagnosis and erroneous diagnosis. Methods: The clinical data of diagnosis and treatment in 3 patients with omohyoid muscle syndrome were summarized retrospectively, and analyzed with the literatures reports. Results: The patients with omohyoid muscle syndrome included 2 males and 1 female; they clinically presented with evident bump of lower sternocleidomastoid muscle

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... during swallowing. All 3 patients underwent surgery, including dissection and lysis of the muscles, cut or resection of the lower belly of the omohyoid muscles. All patients were completely cured without recurrence. Conclusions: Omohyoid muscle syndrome is a rare clinical disease; the misdiagnosis and erroneous diagnosis may be reduced by high recognition to this disease; and this disease can be cured by surgery.