Studies on antitumor activity spectrum of doxycycline

Bo Chen, Hong-gang Zhou, Wei Wang, Wen-guang Gu, Dong Zhao, Peng Wang
2016 Journal of Solid Tumors  
In this study, in vitro (21 kinds of cell lines) and in vivo (four kinds of tumor-bearing mouse models) experiments were performed to determine the anticancer effect of doxycycline. This drug may elicit a strong inhibitory effect on cancer cells and improve the survival condition of mice. This study also preliminarily investigated the inhibitory effect of doxycycline on different kinds of tumor cells.
doi:10.5430/jst.v6n1p103 fatcat:blgzo2oen5glpbz53cvptq2drq