Coordinated Conditional Simulation with SLINK and SUP of Many Markers Linked or Associated to a Trait in Large Pedigrees

Alejandro A. Schäffer, Mathieu Lemire, Jürg Ott, G. Mark Lathrop, Daniel E. Weeks
2011 Human Heredity  
to simulate a much larger number of markers on the same chromosome, linked and possibly associated with a trait locus. We have released new coordinated versions of SLINK (3.0; available from and SUP (v090804; available from or that integrate the two software packages. Thereby, we have removed some of the previous limitations on the joint functionality of the programs, such as the number of founders
more » ... a pedigree. We review the history of SLINK and describe how SLINK and SUP are now coordinated to permit the simulation of large numbers of markers linked and possibly associated with a trait in large pedigrees.
doi:10.1159/000324177 pmid:21734403 pmcid:PMC3136384 fatcat:iql62ds73ze4vjye53cbiyr5jy