Nano-structure zinc and cadmium azide and thiocyanate complexes: Synthesis, characterization, thermal, antimicrobial and DNA interaction
Bulgarian Chemical Communications
Three nano-structure azide and thiocyanate zinc and cadmium complexes of a Schiff base ligand were prepared and characterized by conductivity measurements, elemental analysis, IR, UV-Visible, 1 H and 13 C NMR Spectroscopy and thermo-gravimetric studies. Detectable changes in the spectral data suggested coordination of ligand to zinc and cadmium ions. The proposed formula structure of the complexes was found to be MLX2. Nano-size structure of the complexes was confirmed by transmission electron
... nsmission electron microscopy (TEM). The average particle sizes of the complexes were found to be in the range of 25.32-85.11 nm. Thermal analyses of the complexes was carried out. The thermal curves showed that zinc thiocyanate was decomposed via six thermal steps while cadmium azide and thiocyanate complexes were thermally degraded via three steps. Moreover some activation thermodynamic parameters such as the activation energy, enthalpy, entropy and Gibbs-free energy of activation and the Arrhenius constant were calculated based on TG/DTG curves. The antimicrobial behavior with respect to bacteria of Escherichia coli, Pseudomonas aereuguinosa, Staphylococcus aureus, Bacillus subtillis and a fungus (Candida albicans) was investigated. ZnL(NCS)2 was found to have more antifungal activity against Candida albicans than others. Finally, the interaction of the complexes with DNA (pMalC2X DNA of Escherichia coli) was checked to investigate their cleavage potential.