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Functional Characterization of Gomisin N in High-Fat-Induced Drosophila Obesity Models
2020
International Journal of Molecular Sciences
Gomisin N (GN) is lignin derived from Schisandra chinensis that has been reported to exhibit hepato-protective, anti-cancer, and anti-inflammatory effects. However, its role in whole-body energetic homeostasis remains unclear. In this study, we employed Drosophila melanogaster as a diet-induced obese model to elucidate the effects of GN on lipid and glucose metabolism by measuring climbing activity, triglyceride levels, and lifespan under a rearing condition of a high-fat diet (HFD) containing
doi:10.3390/ijms21197209
pmid:33003580
fatcat:anx5m4dfn5avvhmdutklaagoku