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COMT-by-Sex Interaction Effect on Psychosis Proneness
2015
BioMed Research International
Schizotypy phenotypes in the general population share etiopathogenic mechanisms and risk factors with schizophrenia, supporting the notion of psychosis as a continuum ranging from nonclinical to clinical deviance. Catechol-O-methyltransferase (COMT) is a candidate susceptibility gene for schizophrenia that is involved in the regulation of dopamine in the prefrontal cortex. Several recent studies have reported a sex difference in the impact of COMT genotype on psychiatric and cognitive
doi:10.1155/2015/829237
pmid:25722988
pmcid:PMC4334622
fatcat:dpkadk6h7zhpzkzwfabxo5lv74