Association between alcohol intake and risk for gastric cancer with regard to ALDH2 genotype in the Korean population

C. M. Shin, N. Kim, S.-I. Cho, J. S. Kim, H. C. Jung, I. S. Song
2011 International Journal of Epidemiology  
Conclusions A dose-response association between alcohol intake and the risk for gastric cancer was not observed. However, ALDH2 polymorphisms were found to modify the susceptibility to the development of gastric cancer associated with alcohol intake, especially in case of ALDH2 *1/*2 genotype. The findings suggest an alcohol-ALDH2 genotype interaction in gastric carcinogenesis.
doi:10.1093/ije/dyr067 pmid:21507992 fatcat:i4m3kabgxzhhdc4rzchru7fufq