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Multiple Alignment of Promoter Sequences from the Arabidopsis thaliana L. Genome
2021
Genes
In this study, we developed a new mathematical method for performing multiple alignment of highly divergent sequences (MAHDS), i.e., sequences that have on average more than 2.5 substitutions per position (x). We generated sets of artificial DNA sequences with x ranging from 0 to 4.4 and applied MAHDS as well as currently used multiple sequence alignment algorithms, including ClustalW, MAFFT, T-Coffee, Kalign, and Muscle to these sets. The results indicated that most of the existing methods
doi:10.3390/genes12020135
pmid:33494278
pmcid:PMC7909805
fatcat:v3sc6wlmv5blfikgjbpfz7nydy