Absence of a circulatory transport protein for staphylococcal enterotoxin B

S J Normann, R T Johnsey
1968 Journal of Bacteriology  
Staphylococcal enterotoxin B (SEB) is a lowmolecular weight protein exotoxin which, in minute quantities administered intravenously, is capable of producing nausea, vomiting, hypotension, and death in susceptible laboratory animals. The mechanism of this toxicity is unknown. However, before such questions as cell surface adsorption and biological distribution can be approached properly, the relationship alleged to exist between blood proteins and the toxin must be fully understood. G. J.
more » ... et al. (J. Infect. Diseases 116:48, 1966) have investigated the blood-binding properties of SEB using precipitation methods and have concluded that 90% of intravenously injected SEB is transported in blood as a complex with serum albumin. However, trichloroacetic
doi:10.1128/jb.95.3.1178-1179.1968 fatcat:u3vzggfrxbfmzhzl36dwdfztqq