Tetrodotoxin and Ciona Heart

AKINORI NISHIYAMA, YOHEI SASAKI, TAIZO SUZUKI
1972 Tohoku journal of experimental medicine  
95-96 -The effect of tetrodotoxin on the heart muscle of Ciona intestinalis, a tunicate , was examined since tetrodotoxin is known to abolish the sodium spikes in various excitable tissues by suppressing the sodium conductance . Tetrodotoxin did not influence the shape of action potential of ciona heart even at the concentration of 10-4 g/ml, which is about 10,000 times that effective for the suppression of rate of rise of action potential in frog heart. ciona heart; tetrodotoxin
doi:10.1620/tjem.107.95 fatcat:whvchvpvfret7kxp5vlmqrfzaq