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Inference about causation between body mass index and DNA methylation in blood from a twin family study
[article]
2017
bioRxiv
pre-print
Several studies have reported DNA methylation in blood to be associated with body mass index (BMI), but only a few have investigated causal aspects of the association. We used a twin family design to assess this association at two life points and applied a novel analytical approach to investigate the evidence for causality. Methods: The methylation profile of DNA from peripheral blood was measured for 479 Australian women (mean age 56 years) from 130 twin families. Linear regression was used to
doi:10.1101/223040
fatcat:ogjlybcekbamhch537b2tbgdxu