Could serum albumin value and thrombocyte / lymphocyte ratio be an important prognostic factor in determining the severity of COVID 19?

Emel Uyar, Alparslan Merdİn, Serdar Yamanyar, Mehmet Can EzgÜ, Cumhur Artuk, GÜrhan TaŞkin, Yakup Arslan, Serkan Cerİtlİ
2020 Turkish Journal of Medical Sciences  
Creating potential clinical markers for risk assessment in patients with COVID-19 continues to be an area of interest. In this study, we aimed to evaluate whether serum albumin level and thrombocyte/lymphocyte ratio are related to the severity of the disease. The patients were divided into two groups according to the severity of disease. Demographic data, serum albumin value, lymphocyte count, TLO-1 values (thrombocyte/lymphocyte ratio-1), the highest thrombocyte count during hospitalization,
more » ... O-2 (thrombocyte/lymphocyte ratio-2) values formed by the highest thrombocyte count, was recorded. There was no statistically significant differences (p> 0.05) in terms of gender, thrombocyte count at the time of admission, and highest thrombocyte count during hospital follow-up. There were statistically significant differences in terms of age, comorbidity, lymphocyte value at the time of hospitalization, lymphocyte count during hospital follow-up, TLO I, TLO II, and serum albumin values between the groups. In the ICU group were found to be older, had higher rates of comorbidity, lower lymphocyte values, higher TLO I- II, and lower serum albumin levels (P <0.05) Conclusions: TLO-2 ratio above 260 and lymphocyte level below 1x 103cells/uL, would be a predictor of further intensive care unit need.
doi:10.3906/sag-2008-285 pmid:33350294 fatcat:mchfviwibrfjffhp7jwvrbvvka