INTERNATIONAL JOURNAL OF PHARMACEUTICAL, CHEMICAL AND BIOLOGICAL SCIENCES METAL COMPLEXES: CURRENT TRENDS AND FUTURE POTENTIAL

Prafulla Sabale, Jahanvi Patel, Yogini Patel
IJPCBS   unpublished
Metal ion plays important role in biology which has lead to the development of huge number of metal complexes with diverse therapeutic activity. The advances in the field of chemistry provide better opportunities to use metal complexes as therapeutic agents. Cisplatin, carboplatin and oxaliplatin are the well known metal-based drugs widely used in treatment of cancer. Besides these complexes other metal complexes have shown promising results in the treatment of diseases like diabetes, ulcer,
more » ... diabetes, ulcer, rheumatoid arthritis, inflammatory and cardiovascular diseases etc. This review includes the application of some potential metal complexes in the treatment of various diseases/disorders to improve the therapeutic efficacy of the pharmaceuticals. IJPCBS 2012, 2(3), 251-265 Prafulla M Sabale et al. ISSN: 2249-9504 252 Monodentate: Ligands that bind with a single donor atom to the metal are called monodentate ("one-toothed" ligands): -F, -Cl, -Br, -CN, NH3, H2O IJPCBS 2012, 2(3), 251-265 Prafulla M Sabale et al.
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