Two different devices, InterTAN and proximal femoral nail antirotation (PFNA), have been used in treating intertrochanteric femoral fractures (IFFs). This study was to compare the advantages and disadvantages of InterTAN and PFNA in treating IFFs. Methods: The relevant studies were searched from the database of MEDLINE, Web of Science, EMBASE, Cochrance Library and CNKI. Nineteen randomized controlled trials (RCTs) with 2285 patients were involved in this analysis. Results: Comparing the

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... N with PFNA, harris hip score and fracture healing time of patients with IFFs did not show significant differences (P = 0.133; P = 0.152). However, compared with PFNA, InterTAN seemed to cause more intraoperative blood loss (standardized mean difference, SMD = -1.45; P<0.001) and take more operative time (SMD = -1.95; P<0.001). But postoperative complications of InterTAN were significantly lower than PFNA (odds ratio, OR = 2.22; P<0.001). Conclusions: InterTAN had the same long-term efficacy as PFNA. Although the surgical operation of PFNA surgery had a relative advantage, InterTAN had a low incidence of postoperative complications.