Crystal structure of methyl-4-(4-ethylbenzamido)-2-sulfamoylbenzoate, C17H18N2O5S
Zeitschrift für Kristallographie - New Crystal Structures
Source of material Reagents and solvents used were of commercially available quality. The title compound was prepared similarly to the reported procedure . Dropwise 4-ethylbenzoyl chloride (7.5 mmol) was added to methyl 4-amino-2-sulfamoylbenzoate (7.50 mmol) in THF (20 ml) solution, then refluxed for 4h.Colorless single crystals suitable for X-ray diffraction were obtained by recrystallization from amixture of ethyl acetate and petroleum ether. Experimental details The Hatoms bonded to Cand
... toms bonded to Cand Natoms were positioned geometrically and refined using ar iding model [aliphatic d(C-H) = 0.97(2) Å and d(N-H) =0.86 Å, U iso (H) =1.2 U eq (C)]. The Hatoms bonded to Oatoms were located in difference Fourier maps and refined with O-H distance restraints of 0.85(2) Å and U iso(H) =1.5 Ueq(O). Discussion Amides are very useful starting materials for the synthesis of various bioactive molecules  . These compounds are also widely applied in medicine  and agriculture  . In view of these facts and in continuation of our interest in the agriculture,we attempted to synthesize aseries of amide derivatives, some of which have comparatively high fungicidal activity.