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Sex-specific effects of methylenetetrahydrofolate reductase polymorphisms on schizophrenia with methylation changes
2019
Comprehensive Psychiatry
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Methylenetetrahydrofolate reductase (MTHFR) is the critical enzyme in biotransformation. The polymorphism of MTHFR is a risk factor for schizophrenia. However, whether the MTHFR polymorphism is associated with schizophrenia disease phenotypes and what is the underlying mechanism of MTHFR polymorphism in schizophrenia is under-investigated. In this study, we aim to verify the correlation between MTHFR polymorphisms and clinical features of schizophrenia, while exploring the differential genomic
doi:10.1016/j.comppsych.2019.152121
pmid:31476590
fatcat:uixmc2wxtbczno6fasvsdqok6q