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Targeting VEGFR and FGFR in head and neck squamous cell carcinoma in vitro
2017
Oncology Reports
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease characterized by a tumor microenvironment (TME) that overexpresses vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR), which can lead to neovascularization, tumor growth and metastasis. Therapeutic strategies inhibiting these signaling pathways might lead to innovative HNSCC treatments. Five HNSCC cell lines were characterized based on VEGFR1-3 and FGFR1-4 expression by
doi:10.3892/or.2017.5801
pmid:28714017
fatcat:bbvaeb5taveoxixadc6sgyompq